The Handmade Alphabet is beautifully and humorously illustrated in soft colors with the American Sign Language hand signs for each letter. The hands are pictured interacting with an object that starts with that letter. On the "A" page, the hand making the sign is also holding a stalk of asparagus. The hand for letter "D" holds a dragonfly on the fingertip. The "P" page has fingers dipped in colorful paint.
Laura Rankin has created a multiculturally sensitive book which features a wide variety of skin tones throughout her illustrations.